EGFR ligand-14

CAT: 0931-T212305-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T212305-01Size:10 mg

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CAS Number

1792968-00-3

Target

Ligands for Target Protein for PROTAC, EGFR

Related Pathways

PROTAC, Tyrosine Kinase/Adaptors, Angiogenesis, JAK/STAT signaling

Bioactivity

EGFRligand-14 serves as an EGFR ligand and is utilized in the synthesis of SJF-1521.

Smiles

FC1=CC=CC(=C1)COC2=CC=C(C=C2Cl)NC3=NC=NC4=CC=C(C=C43)C=5C=CC=CC5

Molecular Formula

C27H19ClFN3O

Molecular Weight

455.91

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Chemical Information

N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-phenylquinazolin-4-amine

CAS Number	1792968-00-3
PubChem CID	118370976
IUPAC Name	N-[3-chloro-4-[(3-fluorophenyl)methoxy]phenyl]-6-phenylquinazolin-4-amine
Molecular Formula	C27H19ClFN3O
Molecular Weight	455.9
XLogP	7.2
Topological Polar Surface Area	47
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	6
Heavy Atom Count	33
Formal Charge	0
Complexity	606

SMILES

C1=CC=C(C=C1)C2=CC3=C(C=C2)N=CN=C3NC4=CC(=C(C=C4)OCC5=CC(=CC=C5)F)Cl

InChI

InChI=1S/C27H19ClFN3O/c28-24-15-22(10-12-26(24)33-16-18-5-4-8-21(29)13-18)32-27-23-14-20(19-6-2-1-3-7-19)9-11-25(23)30-17-31-27/h1-15,17H,16H2,(H,30,31,32)

InChIKey

IDRCRUFPWMCBFF-UHFFFAOYSA-N

Chemical Structure

2D Structure

CAS: 1792968-00-3

CID: 118370976

Formula: C27H19ClFN3O

MW: 455.9

Interactive 3D Structure

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View on PubChem Raw 3D data

Computed Properties

Property	Value
Molecular Weight	455.9
XLogP3	7.2
Hydrogen Bond Donor Count	1
Hydrogen Bond Acceptor Count	5
Rotatable Bond Count	6
Exact Mass	455.1200681
Monoisotopic Mass	455.1200681
Topological Polar Surface Area	47 Å²
Heavy Atom Count	33
Formal Charge	0
Complexity	606
Isotope Atom Count	0
Defined Atom Stereocenter Count	0
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Related Products

Catalog	Name
T201728-01	EGFR ligand-11
T86343-01	EGFR ligand-2
T88221-01	EGFR/HER2-IN-14
T17872	E3 ligase Ligand 14
T205198-01	SMARCA2 ligand-14
T205430-01	CRBN ligand-14
T210812-01	IRAK4 ligand-14
T206576-01	BTK ligand-14
T87617-01	VHL Ligand 14
T211487-01	PROTAC EGFR degrader 14

Alternative Products

Catalog	Name
HY-177379	EGFR ligand-14
HY-177380	EGFR ligand-14-PEG3-Boc
HY-178313	EGFR ligand-18
HY-150905	EGFR ligand-2
HY-161537-01	EGFR ligand-9
HY-168305	EGFR ligand-11
HY-161603	EGFR/HER2-IN-14
HY-175252-01	PROTAC EGFR degrader 14
HY-178311	EGFR Ligand-Linker Conjugates 4
MBS5816171	PROTAC PARP/EGFR ligand 1

EGFR ligand-14

Chemical Information

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