Factor B-IN-7

• Description:

  Factor B-IN-7 (Compound (I) ) is a selective Factor B inhibitor. Factor B-IN-7 inhibits Factor B-C3b interaction to suppress complement hyperactivation. Factor B-IN-7 is promising for research of paroxysmal nocturnal hemoglobinuria (PNH), C3 glomerulopathy, and age-related macular degeneration (AMD) associated with complement-mediated diseases[1].

• UNSPSC:

  12352005

• Target:

  Complement System

• Related Pathways:

  Immunology/Inflammation

• Field of Research:

  Inflammation/Immunology

• Smiles:

  COC1=C(C2=C(C(C)=C1)NC=C2)CN3CCC4(C[C@]35CCC6=C5C=CC(C(O)=O)=C6)CC(F)(C4)F

• Molecular Formula:

  C28H30F2N2O3

• Molecular Weight:

  480.55

• References & Citations:

  [1]Chen JY, et al. Crystal form of multi-membered spiro compound, and preparation method therefor and medical use thereof. WO2025185736A1. 2025-10-02.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported