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DX-8951 Hydroxy-acid

CAT: 0804-HY-178239Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-178239Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DX-8951 Hydroxy-acid is a prodrug of phosphoramide. ProAX can effectively increase intracellular ATP levels. DX-8951 Hydroxy-acid activates the AMPK signaling pathway by increasing the AMP/ATP ratio. DX-8951 Hydroxy-acid can enhance mitochondrial function and antioxidant capacity while reducing reactive oxygen species (ROS) levels. DX-8951 Hydroxy-acid has shown significant anti-aging and longevity effects in both human fibroblast and nematode models[1].
CAS Number
276680-63-8
UNSPSC
12352005
Target
AMPK; Drug Metabolite; Reactive Oxygen Species (ROS)
Related Pathways
Epigenetics; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; PI3K/Akt/mTOR
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
FC1=CC2=NC3=C(CN4C3=CC([C@@](C(O)=O)(O)CC)=C(CO)C4=O)C([C@@H](N)CC5)=C2C5=C1C
Molecular Formula
C24H24FN3O5
Molecular Weight
453.46
References & Citations
[1]Anada T, et al. A Nucleic Acid Prodrug That Activates Mitochondrial Respiration, Promotes Stress Resilience, and Prolongs Lifespan. J Am Chem Soc. 2025 Jun 25;147 (25) :22161-22175.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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