Hydroxy-PEG10-acid

• Description :

  Hydroxy-PEG10-acid (HO-PEG10-CH2CH2COOH) is a PEG-based non-cleavable ADC linker that can be used in the synthesis of Antibody-Drug Conjugates (ADCs) [1].

• Product Name Alternative :

  HO-PEG10-CH2CH2COOH

• UNSPSC :

  12352203

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  ADC Linker

• Type :

  ADC Related

• Related Pathways :

  Antibody-drug Conjugate/ADC Related

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Assay Protocol :

  https://www.medchemexpress.com/hydroxy-peg10-acid.html

• Purity :

  99.59

• Solubility :

  10 mM in DMSO

• Smiles :

  O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

• Molecular Formula :

  C23H46O13

• Molecular Weight :

  530.60

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  ADC Related

• Clinical Information :

  No Development Reported

• Isoform :

  PEG Linkers

• CAS Number :

  [2375611-66-6]