Hydroxy-PEG10-acid

• Description:

  Hydroxy-PEG10-acid (HO-PEG10-CH2CH2COOH) is a PEG-based non-cleavable ADC linker that can be used in the synthesis of Antibody-Drug Conjugates (ADCs) [1].

• Product Name Alternative:

  HO-PEG10-CH2CH2COOH

• UNSPSC:

  12352203

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  ADC Linker

• Type:

  ADC Related

• Related Pathways:

  Antibody-drug Conjugate/ADC Related

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/hydroxy-peg10-acid.html

• Purity:

  99.59

• Solubility:

  10 mM in DMSO

• Smiles:

  O=C(O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO

• Molecular Formula:

  C23H46O13

• Molecular Weight:

  530.60

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  ADC Related

• Clinical Information:

  No Development Reported

• Isoform:

  PEG Linkers

• CAS Number:

  [2375611-66-6]