Products for Research Use Only
RegisterLogin

MGB4

CAT: 0804-HY-178174Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-178174Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
MGB4 is a DNA minor groove binder. MGB4 binds to ARE-containing DNA and inhibition of topoisomerase I activity. MGB4 can impacts key cellular pathways, including inhibition oftranslation and alterations in sphingolipid and amino acid metabolism. MGB4 also reduces spermine and spermidine metabolism companied with Doxorubicin. MGB4 can be used for the research of cancer, such as Prostate cancer[1].
UNSPSC
12352100
Target
DNA/RNA Synthesis; Topoisomerase
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C(C1=C(C(C)C)SC(NC(C2=CC(NC(C3=CC(NC(C4=CSC=N4)=O)=CN3C)=O)=CN2C)=O)=N1)NCCCN(C)C.FC(F)(C(O)=O)F
Molecular Formula
C30H36F3N9O6S2
Molecular Weight
739.79
References & Citations
[1]Zenati RA, et al. Untargeted Multiomics of LNCaP Cell Line Treated with a Novel DNA Minor Groove Binder and/or Doxorubicin Using Mass Spectrometry. J Proteome Res. 2025 Oct 3;24 (10) :4911-4924.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Topo I

Related Products

CatalogName
HY-136289MB-VC-MGBA
HY-145287S-MGB-234
HY-U00035-01MGB-BP-3
HY-U00035RMGB-BP-3 (Standard)
HY-145287AS-MGB-234 (TFA)

Alternative Products

CatalogName
GTR19273681-01MGB4
E8ER1910-66H mgB4
E031080H mgB4 Antibody
E45R31577G-1H mgB4 Antibody (Center)
E2120755H mgB4 Rabbit pAb
E55A01358H mgB4 Polyclonal Antibody
E53P12290H mgB4 Rabbit Polyclonal Antibody
E30P4533Recombinant Human H mgB4 Protein
E2613602H mgB4 (Center) Rabbit pAb
E28PE0634H mgB4 (4K9) Mouse Monoclonal antibody

Popular Products