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CDK2-IN-52

CAT: 0804-HY-177957Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-177957Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CDK2-IN-52 (Compound Cpb No 39) is a selective cyclin-dependent kinase 2 (CDK2) inhibitor with a DC50 value of 1-10 nM. CDK2-IN-52 induces cell cycle arrest and suppresses tumor cell proliferation. CDK2-IN-52 is promising for research of CDK2-overexpressing malignancies such as breast and ovarian cancers[1].
CAS Number
[3038638-82-0]
UNSPSC
12352005
Target
CDK
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C1NC(CCN1C2=NN(C)C3=C2C=CC(C4CCN(CC5CCN(CC5)C6=CC=CC(S(=O)(N7CCC(CC7)NC8=NC=C(C=N8)Cl)=O)=C6)CC4)=C3)=O
Molecular Formula
C38H47ClN10O4S
Molecular Weight
775.36
References & Citations
[1]Zhiyong Yu, et al. Bifunctional compounds containing 2,5-substituted pyrimidine derivatives for degrading cyclin-dependent kinase 2 via ubiquitin proteasome pathway. WO2024102849A1. 2024-05-16.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2

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