Antitubercular agent-52

• Description:

  Antitubercular agent-52 (Compound 7k) is an antitubercular agent targeting Mycobacterium tuberculosis (Mtb) . Antitubercular agent-52 selectively inhibits the cytochrome bcc (cyt-bcc) electron transport chain of Mtb and also acts on cytochrome bd (cyt-bd) . Antitubercular agent-52 blocks electron transfer and ATP production by interfering with the key energy metabolism pathway of Mtb. Antitubercular agent-52 is promising for research of tuberculosis[1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Smiles:

  O=C1C2=C(CN(CC3=CC=C(C/N=C/C4=CC=C([N+]([O-])=O)O4)C=C3)C2)NC5=CC=CC=C51

• Molecular Formula:

  C24H20N4O4

• Molecular Weight:

  428.44

• References & Citations:

  [1]Clariano M, et al. Pyrroloquinolone-Based Compounds as a Novel Antimycobacterial Chemotype. ACS Med Chem Lett. 2025 Jun 3;16 (6) :1139-1146.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported