ROR1-IN-2

CAT: 0804-HY-176190Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-176190Size:1 Each
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Description
ROR1-IN-2 (compound 9I) is a potent and selective ROR1 inhibitor. ROR1-IN-2 exhibits antiproliferative activity in multiple cancer cells. ROR1-IN-2 significantly suppresses tumor growth in vivo[1].
UNSPSC
12352005
Target
ROR
Related Pathways
Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CC(NC1=CC=C(C=C1)C2=CC=CC(NC3=C(C=CC(C(NC4=CC5=C(OCCO5)C=C4)=O)=C3)C)=C2)=O
Molecular Formula
C30H27N3O4
Molecular Weight
493.55
References & Citations
[1]Zheng, Q., et al. Structure-directing optimization of N- (2, 3-dihydrobenzo [b][1, 4] dioxin-6-yl) benzamide derivatives as selective receptor tyrosine kinase-like orphan receptor 1 (ROR1) inhibitors for cancer therapy. European Journal of Medicinal Chemistry, 117755.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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