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HDAC6-IN-57

CAT: 0804-HY-176058Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-176058Size:1 Each
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Description
HDAC6-IN-57 (compound 9c) is an HDAC6 inhibitor with an IC50 value of 7 nM. HDAC6-IN-57 inhibits 60 cancer cell lines with a mean GI50 of 2.64 μM while exhibiting significantly lower cytotoxicity towards non-tumor cell lines[1].
UNSPSC
12352005
Target
HDAC
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
O=C(NO)CCCCCCN1CC(N2[C@H](C1=O)CC3=C([C@@H]2C4=CC=CC(Br)=C4)NC5=CC=CC=C53)=O
Molecular Formula
C27H29BrN4O4
Molecular Weight
553.45
References & Citations
[1]Aya Fathy, et al. Development of potent and selective tetrahydro-β-carboline-based HDAC6 inhibitors with promising activity against triple-negative breast cancer. RSC Med Chem. 2025 Apr 17.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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