Products for Research Use Only
RegisterLogin

DPP8/9-IN-1

CAT: 0804-HY-176001Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-176001Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
DPP8/9-IN-1 (Compound 16) is a selective covalent inhibitor of dipeptidyl peptidases 8 and 9 (DPP8/9) with IC50 values of 14 and 298 nM, respectively. DPP8/9-IN-1 binds irreversibly to the active site serine (S730 in DPP9) via a phosphonate warhead and blocks substrate binding to inhibit DPP8/9-mediated protein processing. DPP8/9-IN-1 is promising for research of cancers and inflammatory diseases[1].
UNSPSC
12352005
Target
Dipeptidyl Peptidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer; Inflammation/Immunology
Smiles
N[C@@H]1C(N(P(OCC)(CCSC(C=C2)=CC=C2CCCCC)=O)CCC1)=O
Molecular Formula
C20H33N2O3PS
Molecular Weight
412.53
References & Citations
[1]Sewald L, et al. Sulphostin-inspired N-phosphonopiperidones as selective covalent DPP8 and DPP9 inhibitors. Nat Commun. 2025 Apr 3;16 (1) :3208.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DPP-8; DPP-9

Related Products

CatalogName
HY-175226DPP8/9-IN-2
HY-P701873-01DPP8, Human (sf9)
HY-P88177DPP8 Antibody (YA7861, Mouse)
HY-P701874-01DPP8, Human (sf9, His)
HY-D2327DPP-8/9 probe-1
HY-N10011,9-Caryolanediol 9-acetate
HY-RS24146Dpp8 Rat Pre-designed siRNA Set A
HY-RS17685Dpp8 Mouse Pre-designed siRNA Set A
HY-RS03968DPP8 Human Pre-designed siRNA Set A
HY-157390DPP-4-IN-9

Alternative Products

CatalogName
GTR19258359-01DPP8/9-IN-1
GTR19264304-01DPP8/9-IN-2
BZ0627-1PcDNA3.1-DPP8
CSB-CL744278HUDPP8
DF13999-01DPP8 Antibody
TS405236P5DPP8 CytoSection

Popular Products