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RAPT-37-Me

CAT: 0804-HY-175877Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-175877Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
RAPT-37-Me is a GCN2-targeting agent with IC50 values of 0.002μM, > 10 μM,4.40 μM and 1.31 μM for GCN2, PERK, HRl and PKR, respectively[1].
CAS Number
2396467-34-6
UNSPSC
12352005
Target
Eukaryotic Initiation Factor (eIF)
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C(NC)[C@@]1(C)C[C@H](NC2=NC=C(C3=N2)C(Br)=NN3C(C=C4F)=CC5=C4N=CC=C5)CC1
Molecular Formula
C22H21BrFN7O
Molecular Weight
498.35
References & Citations
[1]Tameire F, et al. In Vivo Tumor Growth Control by General Control Nonderepressible 2-Targeting Agents Results from Kinase Activation. Mol Cancer Ther. 2025 Sep 5:OF1-OF13.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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