USP7-IN-19

• Description:

  USP7-IN-19 is a USP7 inhibitor. USP7-IN-19 can be used for synthesis of PROTAC USP7 Degrader-1 (HY-175358) [1].

• UNSPSC:

  12352005

• Target:

  Deubiquitinase; Ligands for Target Protein for PROTAC

• Related Pathways:

  Cell Cycle/DNA Damage; PROTAC

• Field of Research:

  Cancer

• Smiles:

  O=C1C2=NN(C)C(C3=CC=C(OCC)C=C3)=C2N=CN1CC4(O)CCN(C(C[C@@H](C)C5=CC=CC=C5)=O)CC4

• Molecular Formula:

  C30H35N5O4

• Molecular Weight:

  529.63

• References & Citations:

  [1]Wittenburg S, et al. Enhancing Solubility in VHL-Based PROTACs: Optimized USP7 Degraders for Improved Developability. J Med Chem. 2025 Jul 17.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• Isoform:

  USP7