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MGluR1 activator-1

CAT: 0804-HY-174987Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-174987Size:1 Each
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Description
MGluR1 activator-1 is a stable Vitamin K analogue and a mGluR1 activator that can penetrate the blood-brain barrier. mGluR1 activator-1 exhibits strong transcriptional activation via steroid and xenobiotic receptor as well as retinoic acid receptor. mGluR1 activator-1 induces neuronal differentiation in mouse neural progenitor cells. mGluR1 activator-1 can be used for the study of neurodegenerative disease such as Alzheimer’s[1].
UNSPSC
12352005
Target
MGluR; Steroid Sulfatase
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Smiles
O=C(/C(C)=C/C=C/C(C)=C/CC/C(C)=C/CC1=C(C(C2=C(C1=O)C=CC=C2)=O)C)OC
Molecular Formula
C27H30O4
Molecular Weight
418.52
References & Citations
[1]Hirota Y, et al. A New Class of Vitamin K Analogues Containing the Side Chain of Retinoic Acid Have Enhanced Activity for Inducing Neuronal Differentiation. ACS Chem Neurosci. 2025 Jul 3.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MGluR1

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