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YTHDF2-IN-1

CAT: 0931-T205078-01Size: 10 mgDry Ice: NoHazardous: No
CAT#:0931-T205078-01Size:10 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
Apoptosis
Related Pathways
Apoptosis
Bioactivity
YTHDF2-IN-1 (Compound CK-75) is an inhibitor of YT521-B homology domain family 2 (YTHDF2) with a dissociation constant (Kd) of 26.2 ?M, and it effectively blocks the interaction between YTHDF2 and m6A RNA. It suppresses colony formation in JAR cells and exhibits antiproliferative activity in various cancer cell lines, with an IC50 in the micromolar range. Additionally, YTHDF2-IN-1 induces apoptosis in K562 cells and causes cell cycle arrest at the G0/G1 phase.
Molecular Formula
C21H14N2O4
Molecular Weight
358.35
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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