YTHDF2-IN-1

CAT: 0931-T205078-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T205078-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Apoptosis

Related Pathways

Apoptosis

Bioactivity

YTHDF2-IN-1 (Compound CK-75) is an inhibitor of YT521-B homology domain family 2 (YTHDF2) with a dissociation constant (Kd) of 26.2 μM, and it effectively blocks the interaction between YTHDF2 and m6A RNA. It suppresses colony formation in JAR cells and exhibits antiproliferative activity in various cancer cell lines, with an IC50 in the micromolar range. Additionally, YTHDF2-IN-1 induces apoptosis in K562 cells and causes cell cycle arrest at the G0/G1 phase.

Molecular Formula

C21H14N2O4

Molecular Weight

358.35

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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HY-173008-01	YTHDF2-IN-1
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