PAD-IN-3

CAT: 0804-HY-174349Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-174349Size:1 Each
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Description
PAD-IN-3 (Compound 16) is a potent dual peptidyl arginine deiminases 4 (PAD4) and PAD1 inhibitor with IC50 values of 0.204 μM and 0.273 μM, respectively. PAD-IN-3 is promising for research of citrullination-associated disorders such as cancer and autoimmune diseases[1].
UNSPSC
12352005
Target
Protein Arginine Deiminase
Related Pathways
Epigenetics
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Smiles
OC1=CC2=C(C=C1)C=CC(C(N[C@@H](CCCNC(CCl)=N)C(NCC3=CC=CC=C3)=O)=O)=C2
Molecular Formula
C25H27ClN4O3
Molecular Weight
466.96
References & Citations
[1]Jia Y, et al. Discovery of highly potent naphthalene/quinoline-based PAD inhibitors: Structure-activity relationship, selectivity, and cytotoxicity. Eur J Med Chem. 2025 May 29;296:117830.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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