SEH-IN-3

• Description:

  SEH-IN-3 (Compound 50) is a soluble epoxide hydrolase (sEH) inhibitor (IC50: 0.46 nM) . sEH-IN-3 can maintain the anti-inflammatory and analgesic activities of epoxyeicosatrienoic acids (EETs) [1].

• UNSPSC:

  12352100

• Target:

  Epoxide Hydrolase

• Related Pathways:

  Metabolic Enzyme/Protease

• Field of Research:

  Inflammation/Immunology; Neurological Disease

• Smiles:

  O=C(C1=CN=C(N2CCN(CC3=CC=CC(Cl)=C3)C2=O)S1)NCC4=CC=C(OC)C=C4C(F)(F)F

• Molecular Formula:

  C23H20ClF3N4O3S

• Molecular Weight:

  524.94

• References & Citations:

  [1]Lengerli D, et al. Potent soluble epoxide hydrolase inhibitors based on thiazole-5-carboxamide structure with imidazolidinone moiety as a secondary pharmacophore. Bioorg Chem. 2025 May 29;163:108644.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported