NARS-3′

• Description :

  NARS-3′ is an orally active reversible xanthine oxidase (XO) inhibitor with the IC50 of 21.01 μM. NARS-3′ can competitively inhibit XO activity and reduce uric acid production. NARS-3′ can reduce renal damage in hyperuricemia mice. NARS-3′ can be used for the study of hyperuricemia[1].

• UNSPSC :

  12352100

• Target :

  Xanthine Oxidase

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Smiles :

  O=C1CC(OC2=CC(O)=CC(O)=C12)C3=CC(S(=O)(O[Na])=O)=C(C=C3)O

• Molecular Formula :

  C15H11NaO8S

• Molecular Weight :

  374.30

• References & Citations :

  [1]Luo Y, et al. Xanthine oxidase inhibitory and anti-hyperuricemic properties of sulfonate derivatives of naringenin. Bioorg Chem. 2025 May 20;163:108618.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2702589-46-4]