Products for Research Use Only
RegisterLogin

SFTX-3.3

CAT: 0804-HY-131942Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-131942Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SFTX-3.3 is a Ca2+ channel antagonist with IC50s of approximately 0.24 mM and 0.70 mM against P-type and N-type channels[1][2].
CAS Number
141997-14-0
UNSPSC
12352211
Target
Calcium Channel
Type
Reference compound
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/sftx-3-3.html
Solubility
10 mM in DMSO
Smiles
O=C(NCCCNCCCN)[C@@H](N)CCCNC(N)=N
Molecular Formula
C12H29N7O
Molecular Weight
287.40
References & Citations
[1]Maria Elisa Calcagnotto, et al. An examination of calcium current function on heterotopic neurons in hippocampal slices from rats exposed to methylazoxymethanol. Epilepsia. 2003 Mar;44 (3) :315-21.|[2]T M Norris, et al. Block of high-threshold calcium channels by the synthetic polyamines sFTX-3.3 and FTX-3.3. Mol Pharmacol. 1996 Oct;50 (4) :939-46.|[3]M Fatehi, et al. Polyamine FTX-3.3 and polyamine amide sFTX-3.3 inhibit presynaptic calcium currents and acetylcholine release at mouse motor nerve terminals. Neuropharmacology. 1997 Feb;36 (2) :185-94.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
N-type calcium channel; P/Q-type calcium channel

Related Products

CatalogName
HY-W081226-013,3,3-Trifluoropropionyl chloride
HY-W127810-013,3',3''-Nitrilotripropionic Acid
HY-W4403031,1',3,3,3',3'-Hexamethylindotricarbocyanine (perchlorate)
HY-W1146693- (3- (3-Ethoxy-3-oxopropoxy) propoxy) propanoicacid
HY-D1075-011,1',3,3,3',3'-Hexamethylindodicarbocyanine (iodide)
HY-79034-013,3-Dimethylcyclohexanone
HY-178928KV1.3-IN-3
HY-176547FGFR2/3-IN-3
HY-14611-013,3'-Difluorobenzaldazine
HY-15758-013,3'-Diindolylmethane

Alternative Products

CatalogName
T38854SFTX-3.3
PC68253,3,3-Trifluoropropyl 3,3,3-trifluoropropanoate
QMC01729-013- (3,3,3-Trifluoropropoxy) pyridine
JFC42829-013- (3,3,3-Trifluoropropyl) aniline
sc-2604333- (3,3,3-Trifluoropropyl) heptamethyltrisiloxane
PDC53711-013- (3,3,3-Trifluoropropoxy) piperidine
NU-456S3',3',3'-cAAG
1607393,3,3-Trimethoxypropanenitrile
PC450524-013,3,3-Trifluoropropoxytriethylsilane
JMB17199-013,3,3-Trifluoropropanehydrazide

Popular Products