Anticancer agent 274

• Description :

  Anticancer agent 274 (Compound 1) is a Sorafenib (HY-10201) analog. Anticancer agent 274 can inhibit the growth of tumor cells, with IC50 values of 0.034 μM and 0.042 μM against SaOS-2 and MNNG-HOS cells, respectively. Anticancer agent 274 has relatively low toxicity to normal cells and can be used in the research of tumors such as osteosarcoma[1].

• UNSPSC :

  12352005

• Target :

  Drug Derivative

• Related Pathways :

  Others

• Field of Research :

  Cancer

• Smiles :

  CC(NC1=CC=C(C=C1)OC2=CC=C(C=C2)NC(NC3=CC=CC=C3)=O)=O

• Molecular Formula :

  C21H19N3O3

• Molecular Weight :

  361.39

• References & Citations :

  [1]Maria Dolors PUJOL DILMÉ, et al. Sorafenib analogs for use in the treatment of cancer. WO2025083280A1. 2025-04-24.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported