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HDAC6-IN-59

CAT: 0804-HY-174149Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-174149Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HDAC6-IN-59 (Compound 38k) is a highly selective histone deacetylase 6 (HDAC6) inhibitor (IC50=3.12 nM, with 352-fold selectivity over HDAC1) . HDAC6-IN-59 is promising for research of esophageal cancer[1].
CAS Number
2998932-98-0
UNSPSC
12352005
Target
HDAC
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
O=C(C1=CC=C(CNC2=NC(C3=CC=C(C=C3)Cl)=NN2C4=CC=CC=C4)C=C1)NO
Molecular Formula
C22H18ClN5O2
Molecular Weight
419.86
References & Citations
[1]Zhang X, et al. Structural Optimization of 1,3-Diaryl-1,2,4-triazole-Capped Histone Deacetylase 6 Inhibitors to Obtain Novel Antiesophageal Cancer Candidates. J Med Chem. 2025 Jun 12;68 (11) :10991-11016.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC1; HDAC6

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