PI4Kβ/PKG-IN-1

CAT: 0804-HY-174130Size: 1 EachDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-174130Size:1 Each

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

PI4Kβ/PKG-IN-1 (Compound 19) is an orally active dual inhibitor targeting Plasmodium phosphatidylinositol 4-kinase beta (PI4Kβ) and cGMP-dependent protein kinase (PKG) . PI4Kβ/PKG-IN-1 exhibits potent antiplasmodial activity. PI4Kβ/PKG-IN-1 is promising for research of malaria[1].

UNSPSC

12352005

Target

Parasite; PI4K; PKG

Related Pathways

Anti-infection; PI3K/Akt/mTOR; Stem Cell/Wnt

Field of Research

Infection

Smiles

NC1=NC2=CC(C3=NN(CC4=CC=C(Cl)C(F)=C4)C5=NC=NC(N)=C53)=CC=C2O1

Molecular Formula

C19H13ClFN7O

Molecular Weight

409.80

References & Citations

[1]Gachuhi S, et al. Medicinal Chemistry Progression of Sapanisertib, the Anticancer and Dual Plasmodium Phosphatidylinositol 4-Kinase Beta and cGMP-Dependent Protein Kinase Inhibitor, for Malaria. J Med Chem. 2025 Jun 12;68 (11) :10757-10770.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-174134	PI4Kβ/PKG-IN-2
HY-175732	PI4Kβ-IN-1
HY-106012-01	PI4K-IN-1
HY-178775	PI4K-IN-3
HY-175557	PI4K-IN-2
HY-P1561-01	PKG Substrate
HY-150598-01	CHMFL-PI4K-127
HY-P1292-01	PKG inhibitor peptide
HY-112197-01	PKG drug G1
HY-P1292A	PKG inhibitor peptide (TFA)

Alternative Products

Catalog	Name
GTR19263263-01	PI4Kβ/PKG-IN-1
T211293-01	PI4Kβ/PKG-IN-2
BA8752-10	PI4K-IN-1
GTR19272976-01	PI4Kβ-IN-1
GTR19273507-01	PI4K-IN-3
GTR19264430-01	PI4K-IN-2
C05286-01	PKG-1 Rabbit mAb
YP-W200572-01	Porcine PKG (PKG) ELISA Kit
C18953-50uL	PKG-1 Antibody [B18P19]
20R-1583	PKG antibody

PI4Kβ/PKG-IN-1

Related Products

Alternative Products

Popular Products