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AR ligand 40

CAT: 0804-HY-173498Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-173498Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AR ligand 40 (compound 19c) is an Adenosine A1 Receptor ligand with antagonist activity. AR ligand 40 exhibits antiproliferative effect on SW480, SW48, HCT116, K562, MDA-MB-231, and A549 cells with EC50s of 7, 10, 12, 13, 15 and 39 μM[1].
UNSPSC
12352005
Target
Adenosine Receptor
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
C1(NC2=C3C(N(C4CCCC4)C(C5=CC=CC=C5)=N3)=NC=N2)CCCC1
Molecular Formula
C21H25N5
Molecular Weight
347.46
References & Citations
[1]Córdoba-Gómez LB, et al. Exploring Trisubstituted adenine derivatives as adenosine A1 receptor ligands with antagonist activity: Synthesis, biological evaluation and molecular modelling. Bioorg Chem. 2025 Jun 1;159:108395.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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