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AR ligand-37

CAT: 0804-HY-168697Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-168697Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
AR ligand-37 is a PROTAC target protein ligand that can be used to synthesize BMS-986365.
UNSPSC
12352005
Target
Androgen Receptor; Ligands for Target Protein for PROTAC
Type
Reference compound
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ar-ligand-37.html
Smiles
N#CC1=C(C(F)(F)F)C=C(N2C(N(C3=CC=C(OCCO)C(CC)=C3)C(C)(C)C2=O)=S)C=C1
Molecular Formula
C23H22F3N3O3S
Molecular Weight
477.50
References & Citations
[1]Dana E. Rathkopf, et al. First-in-human phase 1 study of CC-94676, a first-in-class androgen receptor (AR) ligand-directed degrader (LDD), in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC) . JCO 42, 134-134 (2024)
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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