AR ligand 42

• Description:

  AR ligand 42 is a androgen receptor ligand. AR ligand 42 can be used to synthesize androgen receptor PROTAC degrader ITRI-90 (HY-171808) [1].

• UNSPSC:

  12352005

• Target:

  Androgen Receptor; Ligands for Target Protein for PROTAC

• Related Pathways:

  PROTAC; Vitamin D Related/Nuclear Receptor

• Field of Research:

  Endocrinology

• Smiles:

  FC (F) (C1=NN=C2N1N=C (CC2) N3CCC (CC3) C4=CC=C (C=C4) O) F

• Molecular Formula:

  C17H18F3N5O

• Molecular Weight:

  365.35

• References & Citations:

  [1]Hung CL, et al. Targeting androgen receptor and the variants by an orally bioavailable Proteolysis Targeting Chimeras compound in castration resistant prostate cancer. EBioMedicine. 2023 Apr;90:104500.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1240300-27-9