Anticancer agent 272

CAT: 0804-HY-173473Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-173473Size:1 Each
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
Anticancer agent 272 (Compound 2) is an anticancer agent. Anticancer agent 272 has significant anti-bladder cancer cell (T-24) activity (IC50: 2.81 μM) . Anticancer agent 272 consumes glutathione (GSH) through Fenton-like reaction, produces reactive oxygen species (ROS) and hydroxyl radicals (•OH), and induces apoptosis and ferroptosis. Anticancer agent 272 can enhance chemodynamic therapy (CDT) and promote tumor cell death through mitochondrial dysfunction and autophagy. Anticancer agent 272 has potential in the study of bladder cancer[1].
UNSPSC
12352005
Target
Apoptosis; Ferroptosis; Reactive Oxygen Species (ROS)
Related Pathways
Apoptosis; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Field of Research
Cancer
Smiles
BrC1=CN=C(N2[N]([Cu+2]34([Cl-][Cu+2]5([Cl-])([Cl-]4)[N](N6C7=NC=C(C=[N]75)Br)=C(C=C6C(C)C)C(C)C)[Cl-])=C(C=C2C(C)C)C(C)C)[N]3=C1
Molecular Formula
C26H34Br2Cl4Cu2N8
Molecular Weight
887.31
References & Citations
[1]Yang K, et al. Copper (II) Complexes of Pyrazolopyrimidine Derivatives as Anticancer Agents with Enhanced Chemodynamic Therapy through Bimodal Apoptosis and Ferroptosis. J Med Chem. 2025 Apr 10;68 (7) :7137-7152.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-173192Antibacterial agent 272
HY-150571Anticancer agent 76
HY-147782Anticancer agent 67
HY-151092Anticancer agent 77
HY-155543Anticancer agent 135
HY-151888Anticancer agent 92
HY-155570Anticancer agent 137
HY-163808Anticancer agent 237
HY-162575Anticancer agent 231
HY-143302Anticancer agent 31

Alternative Products

CatalogName
M35417-01Anticancer agent 73
T72487-01Anticancer agent 99
T83073-01Anticancer agent 96
T83077-01Anticancer agent 86
T83091-01Anticancer agent 113
T83092-01Anticancer agent 112
T83093-01Anticancer agent 107
T78958-01Anticancer agent 106
T79202-01Anticancer agent 118
T79465-01Anticancer agent 135

Popular Products