8-BuS-AMP

• Description :

  8-BuS-AMP is a CD39 and CD73 dual inhibitor. 8-BuS-AMP inhibits human CD39, mouse CD39 and human CD73 with Kis of 0.292, 2.19 and 1.19 μM, respectively[1].

• UNSPSC :

  12352005

• Target :

  NTPDase

• Related Pathways :

  Immunology/Inflammation

• Field of Research :

  Cancer

• Purity :

  99.90

• Solubility :

  H2O : 50 mg/mL (ultrasonic)

• Smiles :

  O[C@H]1[C@@H](O)[C@H](N2C(N=CN=C3N)=C3N=C2SCCCC)O[C@@H]1COP(O)(O)=O

• Molecular Formula :

  C14H22N5O7PS

• Molecular Weight :

  435.39

• References & Citations :

  [1]Bi C, et al. Synthesis, Characterization, Interactions, and Immunomodulatory Function of Ectonucleotidase CD39/CD73 Inhibitor 8-Butylthioadenosine 5'-Monophosphate. ACS Pharmacol Transl Sci. 2025 Apr 3;8 (5) :1401-1415.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [344402-39-7]