ARCher-142

• Description :

  ARCher-142 (compound S8) is a potent tankyrase inhibitor. ARCher-142 selectively binds to ARC4 with potency of 8 µM[1].

• UNSPSC :

  12352005

• Target :

  PARP

• Related Pathways :

  Cell Cycle/DNA Damage; Epigenetics

• Field of Research :

  Cancer

• Smiles :

  CCC(CCCN1C(C(O)=C(C1C2=CC=C(C=C2)O)C(C3=CC=C4OCCOC4=C3)=O)=O)CC

• Molecular Formula :

  C27H31NO6

• Molecular Weight :

  465.54

• References & Citations :

  [1]Bosetti, C., et al. Discovery of Tankyrase scaffolding inhibitor specifically targeting the ARC4 peptide binding domain. bioRxiv, 2025-03.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported