Products for Research Use Only
RegisterLogin

H 142

CAT: 0931-T25479-01Size: 100 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T25479-01Size:100 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
85139-12-4
Target
Others
Related Pathways
Others
Bioactivity
H 142 is a human renin decapeptide inhibitor.
Smiles
C([C@H](CC1=CN=CN1)NC(=O)[C@@H]2CCCN2)(=O)N3[C@H](C(N[C@@H](CC4=CC=CC=C4)C(N[C@@H](CC5=CN=CN5)C(N[C@H](CN[C@H](C(N[C@H](C(N[C@@H](CC6=CN=CN6)C(N[C@@H](CCCCN)C(O)=O)=O)=O)[C@H](CC)C)=O)C(C)C)CC(C)C)=O)=O)=O)CCC3
Molecular Formula
C60H91N17O10
Molecular Weight
1210.47
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

H 142

decapeptide inhibitor of human renin; RN given refers to all L-isomer

CAS Number85139-12-4
PubChem CID134897
IUPAC Name(2S)-6-amino-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S,3S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-2-[[(2S)-1-[(2S)-3-(1H-imidazol-5-yl)-2-[[(2S)-pyrrolidine-2-carbonyl]amino]propanoyl]pyrrolidine-2-carbonyl]amino]-3-phenylpropanoyl]amino]propanoyl]amino]-4-methylpentyl]amino]-3-methylbutanoyl]amino]-3-methylpentanoyl]amino]propanoyl]amino]hexanoic acid
Molecular FormulaC60H91N17O10
Molecular Weight1210.5
XLogP0.2
Topological Polar Surface Area397
Hydrogen Bond Donor Count14
Hydrogen Bond Acceptor Count16
Rotatable Bond Count36
Heavy Atom Count87
Formal Charge0
Complexity2240
SMILES
CC[C@H](C)[C@@H](C(=O)N[C@@H](CC1=CN=CN1)C(=O)N[C@@H](CCCCN)C(=O)O)NC(=O)[C@H](C(C)C)NC[C@H](CC(C)C)NC(=O)[C@H](CC2=CN=CN2)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@@H]4CCCN4C(=O)[C@H](CC5=CN=CN5)NC(=O)[C@@H]6CCCN6
InChI
InChI=1S/C60H91N17O10/c1-7-37(6)51(58(84)74-47(26-40-29-63-33-68-40)55(81)71-44(60(86)87)17-11-12-20-61)76-57(83)50(36(4)5)66-31-42(23-35(2)3)70-53(79)46(25-39-28-62-32-67-39)72-54(80)45(24-38-15-9-8-10-16-38)73-56(82)49-19-14-22-77(49)59(85)48(27-41-30-64-34-69-41)75-52(78)43-18-13-21-65-43/h8-10,15-16,28-30,32-37,42-51,65-66H,7,11-14,17-27,31,61H2,1-6H3,(H,62,67)(H,63,68)(H,64,69)(H,70,79)(H,71,81)(H,72,80)(H,73,82)(H,74,84)(H,75,78)(H,76,83)(H,86,87)/t37-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-/m0/s1
InChIKey
XIZSMQBWVQNHCA-NIRMQQKASA-N
Chemical Structure
2D Structure
2D structure of H 142
CAS: 85139-12-4
CID: 134897
Formula: C60H91N17O10
MW: 1210.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight1210.5
XLogP30.2
Hydrogen Bond Donor Count14
Hydrogen Bond Acceptor Count16
Rotatable Bond Count36
Exact Mass1209.71348217
Monoisotopic Mass1209.71348217
Topological Polar Surface Area397 Ų
Heavy Atom Count87
Formal Charge0
Complexity2240
Isotope Atom Count0
Defined Atom Stereocenter Count11
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
T204227-01EGFR-IN-142
T15479-01HFI-142
T207348-01ARCher-142
T79843-01Anticancer agent 142
T33426-01MK-142 dimethanesulfonate
T74820-01Antibacterial agent 142
T80374-01HBA (111–142)
T2062-01Kb NB 142-70
T203021-01E3 Ligase Ligand-linker Conjugate 142
TP3403-01Microtubule-Associated Protein (142-161) (human)

Alternative Products

CatalogName
TBI3024-25MGAc-Leu-Leu-Nle-CHO (ALLN), Calpain inhibitor
TBS10340-0.5MGInVivo Mouse IgG1 Isotype Control Antibody
TBS10338-0.5MGInVivo Anti-Mouse CD161/KLRB1/NK1.1 Antibody
TBS10336-1MGInVivoMAb Anti-Human Flt3 ligand/FLT3LG Antibody
TBS10334-0.5MGInVivo Anti-Human CDH17/Cadherin-17 Monoclonal Antibody
TBS10333-1MGInVivo Anti-Phosphotyrosine Monoclonal Antibody
TBS42064-100Clostridium butyricum qPCR Detection Kit
TBI5887-25MGRo 5-3335, RUNX1 inhibitor
TBI5778-5MGSBI-797812, NAMPT activator
TBI5468-25MGPyrintegrin, ß1-integrin agonist

Popular Products