HFI-142

• Description :

  HFI-142 is an insulin-regulated aminopeptidase (IRAP) inhibitor with a Ki of 2.01 μM[1].

• UNSPSC :

  12352005

• Hazard Statement :

  H302-H315-H319-H335

• Target :

  Aminopeptidase

• Type :

  Reference compound

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/hfi-142.html

• Purity :

  99.55

• Solubility :

  DMSO : 125 mg/mL (ultrasonic)

• Smiles :

  CCOC(C1=C(N)OC2=CC(O)=CC=C2C1C3=CN=CC=C3)=O

• Molecular Formula :

  C17H16N2O4

• Molecular Weight :

  312.32

• Precautions :

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

• References & Citations :

  [1]Albiston AL, et al. Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobicpacking point at the active site of insulin-regulated aminopeptidase. Mol Pharmacol. 2010 Oct;78 (4) :600-7.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [332164-34-8]