HFI-142

• Description:

  HFI-142 is an insulin-regulated aminopeptidase (IRAP) inhibitor with a Ki of 2.01 μM[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302-H315-H319-H335

• Target:

  Aminopeptidase

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/hfi-142.html

• Purity:

  99.55

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)

• Smiles:

  CCOC(C1=C(N)OC2=CC(O)=CC=C2C1C3=CN=CC=C3)=O

• Molecular Formula:

  C17H16N2O4

• Molecular Weight:

  312.32

• Precautions:

  P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362-P403+P233-P405-P501

• References & Citations:

  [1]Albiston AL, et al. Phenylalanine-544 plays a key role in substrate and inhibitor binding by providing a hydrophobicpacking point at the active site of insulin-regulated aminopeptidase. Mol Pharmacol. 2010 Oct;78 (4) :600-7.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [332164-34-8]