GPR40 Activator 3

• Description :

  GPR40 Activator 3 (compound SC) is a potent GPR40 activator. GPR40 Activator 3 mitigates pulmonary fibrosis by inhibiting M2 macrophage polarization via the GPR40/PKD1/CD36 axis[1].

• UNSPSC :

  12352005

• Target :

  Free Fatty Acid Receptor

• Related Pathways :

  GPCR/G Protein

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Metabolic Disease

• Smiles :

  O=C1C2=C(OC3=C1C(OC)=CC=C3)C=C(O)C=C2O

• Molecular Formula :

  C14H10O5

• Molecular Weight :

  258.23

• References & Citations :

  [1]Wan HQ, et al. GPR40 activation alleviates pulmonary fibrosis by repressing M2 macrophage polarization through the PKD1/CD36/TGF-β1 pathway. Acta Pharmacol Sin. 2025 May 14.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2980-31-6]