BTK-IN-43

• Description:

  BTK-IN-43 (compound 9) is an inhibitor of BTK with an IC50 value of 21.6 nM. BTK-IN-43 has oral activity[1].

• UNSPSC:

  12352005

• Target:

  Btk

• Related Pathways:

  Protein Tyrosine Kinase/RTK

• Field of Research:

  Cancer

• Smiles:

  CC(O)(C1=CC2=C(N3C(C4=CC=CC(N5C(NC6=C(C5=O)C=CC=C6F)=O)=C4F)=CC=C3C(N2)=O)C=C1)C

• Molecular Formula:

  C28H20F2N4O4

• Molecular Weight:

  514.48

• References & Citations:

  [1]Chaoquan Tian, et al. Design, Synthesis, and Biological Evaluation of Pyrrolo[1,2- a]quinoxalin-4 (5 H) -one Derivatives as Potent and Orally Available Noncovalent Bruton's Tyrosine Kinase (BTK) Inhibitors. J Med Chem. 2025 Apr 24;68 (8) :8841-8860.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [3081685-04-0]