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BTK-IN-43

CAT: 0804-HY-172589Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-172589Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BTK-IN-43 (compound 9) is an inhibitor of BTK with an IC50 value of 21.6 nM. BTK-IN-43 has oral activity[1].
CAS Number
3081685-04-0
UNSPSC
12352005
Target
Btk
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
CC(O)(C1=CC2=C(N3C(C4=CC=CC(N5C(NC6=C(C5=O)C=CC=C6F)=O)=C4F)=CC=C3C(N2)=O)C=C1)C
Molecular Formula
C28H20F2N4O4
Molecular Weight
514.48
References & Citations
[1]Chaoquan Tian, et al. Design, Synthesis, and Biological Evaluation of Pyrrolo[1,2- a]quinoxalin-4 (5 H) -one Derivatives as Potent and Orally Available Noncovalent Bruton's Tyrosine Kinase (BTK) Inhibitors. J Med Chem. 2025 Apr 24;68 (8) :8841-8860.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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