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DPP9-IN-1

CAT: 0804-HY-172529Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-172529Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DPP9-IN-1 (Compound 42) is a dipeptidyl peptidase 9 (DPP9) inhibitor with IC50 of 3 nM for DPP9 and 0.6 μM for DPP8. DPP9-IN-1 induces concentration-dependent LDH release in THP-1 cells[1].
CAS Number
[3020859-03-1]
UNSPSC
12352005
Target
Dipeptidyl Peptidase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease; Neurological Disease
Smiles
FC(C(F)=C1)=CC(C2)=C1CN2C(CN[C@@]3(C4)C[C@@H](C5)C[C@H]4C[C@]5(NC(OC(C)(C)C)=O)C3)=O
Molecular Formula
C25H33F2N3O3
Molecular Weight
461.54
References & Citations
[1]Siham Benramdane, et al. Highly Selective Inhibitors of Dipeptidyl Peptidase 9 (DPP9) Derived from the Clinically Used DPP4-Inhibitor Vildagliptin. J Med Chem. 2023 Sep 28;66 (18) :12717-12738.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DPP-8; DPP-9

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