JNJ-2901

• Description:

  JNJ-2901 is an inhibitor of M. tuberculosis cytochrome bc1:aa3. JNJ-2901 reduces bacterial load in the acute/chronic mouse infection models of M. tuberculosis H37Rv-ΔcydAB. JNJ-2901 can be used in tuberculosis (TB) research[1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Smiles:

  CCC1=C(N2C=C(C=CC2=N1)Cl)C(NCC3=CC=C(C=C3)C4CC5(CN(C5)S(=O)(C(F)(F)F)=O)C4)=O

• Molecular Formula:

  C24H24ClF3N4O3S

• Molecular Weight:

  540.99

• References & Citations:

  [1]Verma AK, et al. Structural and mechanistic study of a novel inhibitor analogue of M. tuberculosis cytochrome bc1:aa3. NPJ Drug Discov. 2025;2 (1) :6. doi: 10.1038/s44386-025-00008-3. Epub 2025 Apr 2. PMID: 40191462; PMCID: PMC11964921.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [2059985-55-4]