INCB-056868

CAT: 0804-HY-172233Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-172233Size:1 Each
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Description
INCB-056868 is the metabolite M11 of Epacadostat (HY-15689) . INCB-056868 can also serve as a substrate for BCRP. INCB-056868 is promising for research of metabolic diseases[1].
CAS Number
[2252320-89-9]
UNSPSC
12352211
Target
BCRP; Drug Metabolite
Related Pathways
Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=S(N)(NCCNC1=NON=C1C(NC2=CC=C(C(Br)=C2)F)=N)=O
Molecular Formula
C11H13BrFN7O3S
Molecular Weight
422.23
References & Citations
[1]Zhang Q, et al. In Vitro Interactions of Epacadostat and its Major Metabolites with Human Efflux and Uptake Transporters: Implications for Pharmacokinetics and Drug Interactions. Drug Metab Dispos. 2017 Jun;45 (6) :612-623.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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