INCB-056868

• Description:

  INCB-056868 is the metabolite M11 of Epacadostat (HY-15689) . INCB-056868 can also serve as a substrate for BCRP. INCB-056868 is promising for research of metabolic diseases[1].

• UNSPSC:

  12352211

• Target:

  BCRP; Drug Metabolite

• Related Pathways:

  Membrane Transporter/Ion Channel; Metabolic Enzyme/Protease

• Applications:

  Metabolism-protein/nucleotide metabolism

• Field of Research:

  Metabolic Disease

• Smiles:

  O=S(N)(NCCNC1=NON=C1C(NC2=CC=C(C(Br)=C2)F)=N)=O

• Molecular Formula:

  C11H13BrFN7O3S

• Molecular Weight:

  422.23

• References & Citations:

  [1]Zhang Q, et al. In Vitro Interactions of Epacadostat and its Major Metabolites with Human Efflux and Uptake Transporters: Implications for Pharmacokinetics and Drug Interactions. Drug Metab Dispos. 2017 Jun;45 (6) :612-623.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2252320-89-9