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LSQ-28

CAT: 0804-HY-172136Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-172136Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
LSQ-28 is an orally active HDAC3 inhibitor with an IC50 of 42 nM, and exhibits potent anticancer, antiproliferative, antimigratory, anti-invasive, and antiwound healing activities. LSQ-28 can be utilized in cancer research[1].
UNSPSC
12352005
Target
HDAC
Related Pathways
Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
CCCNNC(C1=CC=C(CN2C3=C(C4=CC=CC=C24)C(C5=CC=CC=N5)=NC6=C3C=CC=C6)C=C1)=O
Molecular Formula
C31H27N5O
Molecular Weight
485.58
References & Citations
[1]Li S, et al. Discovery of Highly Potent and Orally Bioavailable Histone Deacetylase 3 Inhibitors as Immunomodulators and Enhancers of DNA-Damage Response in Cancer Therapy. J Med Chem. 2025 Jan 28.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
HDAC3

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