Thalidomide-4-piperidineacetaldehyde

• Description:

  Thalidomide-4-piperidineacetaldehyde is an E3 ligase ligand and linker conjugate and can be used to synthesize PROTAC H122 (HY-172113) [1].

• UNSPSC:

  12352005

• Target:

  E3 Ligase Ligand-Linker Conjugates

• Related Pathways:

  PROTAC

• Field of Research:

  Others

• Smiles:

  O=C(CC1)NC(C1N(C2=O)C(C(C2=C3)=CC=C3N(CC4)CCC4CC=O)=O)=O

• Molecular Formula:

  C20H21N3O5

• Molecular Weight:

  383.40

• References & Citations:

  [1]Lu Y, et al. Selective Degradation of TEADs by a PROTAC Molecule Exhibited Robust Anticancer Efficacy In Vitro and In Vivo. J Med Chem. 2025 Jan 13.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2222115-36-6