3′-Deoxy CTP

• Description :

  3′-Deoxy CTP is a nucleotide analogue and a mandatory chain terminator. 3′-Deoxy CTP can cause chain termination by lacking the 3′-hydroxyl group, inhibiting the RNA synthesis activity of HCV nonstructural protein (NS5B) polymerase and blocking viral replication. 3′-Deoxy CTP can be used to study the chain termination mechanism of HCV polymerase and the development of antiviral drugs[1].

• CAS Number :

  [69383-05-7]

• UNSPSC :

  12352005

• Target :

  HCV

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-anti-virus

• Field of Research :

  Infection

• Smiles :

  O[C@@H]1C[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O[C@H]1N2C(N=C(N)C=C2)=O

• Molecular Formula :

  C9H16N3O13P3

• Molecular Weight :

  467.16

• References & Citations :

  [1]Deval J, et al. Pyrophosphorolytic excision of nonobligate chain terminators by hepatitis C virus NS5B polymerase. Antimicrob Agents Chemother. 2007 Aug;51 (8) :2920-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported