3′-Deoxy CTP

• Description:

  3′-Deoxy CTP is a nucleotide analogue and a mandatory chain terminator. 3′-Deoxy CTP can cause chain termination by lacking the 3′-hydroxyl group, inhibiting the RNA synthesis activity of HCV nonstructural protein (NS5B) polymerase and blocking viral replication. 3′-Deoxy CTP can be used to study the chain termination mechanism of HCV polymerase and the development of antiviral drugs[1].

• UNSPSC:

  12352005

• Target:

  HCV

• Related Pathways:

  Anti-infection

• Applications:

  COVID-19-anti-virus

• Field of Research:

  Infection

• Smiles:

  O[C@@H]1C[C@@H](COP(OP(OP(O)(O)=O)(O)=O)(O)=O)O[C@H]1N2C(N=C(N)C=C2)=O

• Molecular Formula:

  C9H16N3O13P3

• Molecular Weight:

  467.16

• References & Citations:

  [1]Deval J, et al. Pyrophosphorolytic excision of nonobligate chain terminators by hepatitis C virus NS5B polymerase. Antimicrob Agents Chemother. 2007 Aug;51 (8) :2920-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [69383-05-7]