CK1?-IN-9

• Target:

  Casein Kinase|||p38 MAPK

• Related Pathways:

  MAPK|||Stem Cells|||Metabolism

• Bioactivity:

  CK1?-IN-9 (Compound 8) is an inhibitor of casein kinase 1 (CK1), specifically targeting CK1? with an IC50 of 1.4 nM. The compound also inhibits p38? and p38? with IC50 values of 0.25 ?M and 0.78 ?M, respectively. CK1?-IN-9 exhibits favorable pharmacokinetic properties, including high oral bioavailability (70%) and moderate clearance.

• Smiles:

  FC=1C=CC (=CC1) C2=NN (C=C2C=3C=CN=C4NN=CC43) C

• Molecular Formula:

  C16H12FN5

• Molecular Weight:

  293.298

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  3057263-82-5