Pyrone-211

• Description:

  Pyrone-211 is a potent GPR84 agonist and AKR1C3 inhibitor. Pyrone-211 participates in an expanded polyamine pathway[1].

• UNSPSC:

  12352005

• Target:

  Aldose Reductase; GPR84

• Related Pathways:

  GPCR/G Protein; Metabolic Enzyme/Protease

• Field of Research:

  Metabolic Disease

• Purity:

  99.32

• Smiles:

  O=C1OC (CCCCCCC) =CC (O) =C1

• Molecular Formula:

  C12H18O3

• Molecular Weight:

  210.27

• References & Citations:

  [1]Dudkina N, et al. Human AKR1C3 binds agonists of GPR84 and participates in an expanded polyamine pathway. Cell Chem Biol. 2025 Jan 16;32 (1) :126-144.e18.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, protect from light)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  90632-45-4