Pyrone-211

• Description :

  Pyrone-211 is a potent GPR84 agonist and AKR1C3 inhibitor. Pyrone-211 participates in an expanded polyamine pathway[1].

• UNSPSC :

  12352005

• Target :

  Aldose Reductase; GPR84

• Related Pathways :

  GPCR/G Protein; Metabolic Enzyme/Protease

• Field of Research :

  Metabolic Disease

• Purity :

  99.32

• Smiles :

  O=C1OC(CCCCCCC)=CC(O)=C1

• Molecular Formula :

  C12H18O3

• Molecular Weight :

  210.27

• References & Citations :

  [1]Dudkina N, et al. Human AKR1C3 binds agonists of GPR84 and participates in an expanded polyamine pathway. Cell Chem Biol. 2025 Jan 16;32 (1) :126-144.e18.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [90632-45-4]