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PROTAC ER Degrader-15

CAT: 0804-HY-170332Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-170332Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PROTAC ER Degrader-15 (Compound 40) is an orally active degrader of the estrogen receptor (ER) with anticancer activity, which can be used in breast cancer research (Pink: Target Protein Ligand ; Black: Linker (HY-30756) ; Blue: E3 Ligase Ligand (HY-138793) ; E3 Ligase Ligand-Linker Conjugate (HY-169979) ).
UNSPSC
12352005
Target
Estrogen Receptor/ERR; PROTACs
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
OC1=CC=C2C(OC[C@H](C3=C(F)C=CC=C3F)[C@@H]2C4=CC(F)=C(N5CCC(CN6CCC7(CN(C8=CC=C(C(N(C9C(NC(CC9)=O)=O)C%10)=O)C%10=C8)C7)CC6)CC5)C(F)=C4)=C1
Molecular Formula
C47H47F4N5O5
Molecular Weight
837.90
References & Citations
[1]Du wu, et al. Aromatic compound, method for preparing same, and use thereof in preparation of estrogen receptor degrader. Patent, WO2023241598, 2023-12-21.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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