4-TM.P

• Description :

  4-TM.P binds to the minor groove of DNA, inhibits proliferation of cancer cell K562 with an IC50 of 25 µM, arrests the cell cycle at G0/G1 phase, and induces apoptosis in cell K562. 4-TM.P can be used in anti-leukemia research[1].

• UNSPSC :

  12352005

• Target :

  Apoptosis

• Related Pathways :

  Apoptosis

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Cancer

• Smiles :

  O=C(C1=NC=CN=C1)OC(C)/C=C/C2=C(C)CCCC2(C)C

• Molecular Formula :

  C18H24N2O2

• Molecular Weight :

  300.40

• References & Citations :

  [1]Jahanbakhsh K, et al., DNA binding, and apoptosis-inducing activities of a β-ionone-derived ester in human myeloid leukemia cells: multispectral and molecular dynamic simulation analyses. Sci Rep. 2024 Nov 14;14 (1) :27985.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [2089575-84-6]