4-TM.P

• Description:

  4-TM.P binds to the minor groove of DNA, inhibits proliferation of cancer cell K562 with an IC50 of 25 µM, arrests the cell cycle at G0/G1 phase, and induces apoptosis in cell K562. 4-TM.P can be used in anti-leukemia research[1].

• UNSPSC:

  12352005

• Target:

  Apoptosis

• Related Pathways:

  Apoptosis

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Smiles:

  O=C(C1=NC=CN=C1)OC(C)/C=C/C2=C(C)CCCC2(C)C

• Molecular Formula:

  C18H24N2O2

• Molecular Weight:

  300.40

• References & Citations:

  [1]Jahanbakhsh K, et al., DNA binding, and apoptosis-inducing activities of a β-ionone-derived ester in human myeloid leukemia cells: multispectral and molecular dynamic simulation analyses. Sci Rep. 2024 Nov 14;14 (1) :27985.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2089575-84-6