SL-89.0591

• Description :

  SL-89.0591 is a uroselective α1-adrenoceptor antagonist. SL-89.0591 exhibits a more potent blocking effect on urethral receptors than on vascular receptors in anesthetized rabbits, with a lower risk of orthostatic hypotension. SL-89.0591 can be used in research related to benign prostatic hyperplasia[1].

• CAS Number :

  [194674-19-6]

• UNSPSC :

  12352005

• Target :

  Adrenergic Receptor

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Smiles :

  NC(C1=CC=NC(NCCCN2CCN(C3=C(OC)C=CC(Cl)=C3)CC2)=N1)=O

• Molecular Formula :

  C19H25ClN6O2

• Molecular Weight :

  404.89

• References & Citations :

  [1]Hieble JP, et al. Effects of alpha1-adrenoceptor antagonists on agonist and tilt-induced changes in blood pressure: relationships to uroselectivity. Eur J Pharmacol. 1999 May 28;373 (1) :51-62.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  Phase 2

• Isoform :

  α adrenergic receptor