SL-176

• Description :

  SL-176, a WIP1 inhibitor, induces cell cycle arrest and apoptosis when combined with GSK-J4 (HY-15648B), thereby suppressing tumor growth both in vitro and in vivo[1].

• UNSPSC :

  12352211

• Target :

  Apoptosis; Phosphatase

• Related Pathways :

  Apoptosis; Metabolic Enzyme/Protease

• Field of Research :

  Cancer

• Smiles :

  CC[Si](CC)(CC)O[C@@H]1CCC[C@@]2([H])[C@@](C(O)=O)(C)C[C@@H](O[Si](C)(C(C)(C)C)C)C[C@@]21[H]

• Molecular Formula :

  C24H48O4Si2

• Molecular Weight :

  456.81

• References & Citations :

  [1]Treis D, et al. Targeted inhibition of WIP1 and histone H3K27 demethylase activity synergistically suppresses neuroblastoma growth. Cell Death Dis. 2025 Apr 19;16 (1) :318.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1809556-48-6]