Products for Research Use Only
RegisterLogin

Terutroban (sodium)

CAT: 0804-HY-16991A-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-16991A-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Terutroban (S-18886) sodium is a selective and orally active thromboxane-prostaglandin (TP) receptor antagonist with an IC50 of 16.4 nM. Terutroban sodium inhibits TXA2 and prostaglandin endoperoxide receptors. Terutroban sodium is a potent antithrombotic agent and possesses anti-atherosclerotic and anti-vasoconstrictor properties[1][2][3].
CAS Number
609340-89-8
Product Name Alternative
S-18886 (sodium)
UNSPSC
12352005
Target
Prostaglandin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease; Metabolic Disease
Purity
99.78
Solubility
10 mM in DMSO
Smiles
O=C(O[Na])CCC1=C2CC[C@@H](NS(=O)(C3=CC=C(Cl)C=C3)=O)CC2=CC=C1C
Molecular Formula
C20H21ClNNaO4S
Molecular Weight
429.89
References & Citations
[1]Wang X, et al. Potent, long-acting cyclopentane-1,3-Dione thromboxane (A2) -receptor antagonists. ACS Med Chem Lett. 2014 Jul 24;5 (9) :1015-20.|[2]Gelosa P, et al. Terutroban, a thromboxane/prostaglandin endoperoxide receptor antagonist, prevents hypertensive vascular hypertrophy and fibrosis. Am J Physiol Heart Circ Physiol. 2011 Mar;300 (3) :H762-8.|[3]Lesault PF, et al. Daily administration of the TP receptor antagonist terutroban improved endothelial function in high-cardiovascular-risk patients with atherosclerosis. Br J Clin Pharmacol.2011 Jun;71 (6) :844-851.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 3

Related Products

CatalogName
HY-16991-01Terutroban
HY-16991RTerutroban (Standard)
HY-N15194AInostamycin A (sodium)
HY-166084Docosatetraenoate (sodium)
HY-16366ABriciclib (sodium)
HY-150364AFarabursen (sodium)
HY-107943Tyropanoate (sodium)
HY-W009640AMofebutazone (sodium)
HY-22274-01DMPG (sodium)
HY-17474A-01Parecoxib (Sodium)

Alternative Products

CatalogName
GTR19274122-01Terutroban sodium
461622Terutroban
A20884-100Terutroban 100mg
A20884-25Terutroban 25mg
A20884-50Terutroban 50mg
A20884-10Terutroban 10mg
A20884-5Terutroban 5mg
A20884-10mM-DTerutroban 10mM * 1mL in DMSO
1191110 500Sodium Metabisulphite (Sodium Disulphite, Sodium Pyrosulphite)
RM-T081600-01Thiopental Sodium And Sodium Carbonate

Popular Products