NSC 645827

• Description :

  NSC 645827 is an inhibitor for NAD (P) H: quinone oxidoreductase 1 (NQO1) with an IC50 of 0.7 μM[1].

• UNSPSC :

  12352005

• Target :

  Quinone Reductase

• Related Pathways :

  Metabolic Enzyme/Protease

• Field of Research :

  Cancer

• Smiles :

  O=C1C2=CC(O)=CC=C2N3N=NC4=C3C1=C(NCCN(C)C)C=C4

• Molecular Formula :

  C17H17N5O2

• Molecular Weight :

  323.35

• References & Citations :

  [1]Jianwen Wang, et al. Identification and structure-guided development of triazole urea-based selective antagonists of Arabidopsis karrikin signaling. Nat Commun. 2025 Jan 2;16 (1) :104.|[2]Chee S M. Design, Synthesis and Biological Evaluation of the Novel Inhibitors of Enzymes NQO1 and NQO2[M]. The University of Manchester (United Kingdom), 2014.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [128113-19-9]