PAR-2-IN-2

• Description:

  PAR-2-IN-2 (compound P-596) is a protease-activated receptor 2 (PAR-2) inhibitor with an IC50 of 10.79 μM for SLIGKV and an IC50 of greater than 200 μM for Trypsin[1].

• UNSPSC:

  12352005

• Target:

  Protease Activated Receptor (PAR) ; Ser/Thr Protease

• Related Pathways:

  GPCR/G Protein; Metabolic Enzyme/Protease

• Field of Research:

  Inflammation/Immunology

• Smiles:

  O=C(N1CCN(CC1)C(C2=CC=CC=C2)=O)C3=NN4C(N=C(C5=CC=CC=C5)C=C4C(F)(F)F)=C3

• Molecular Formula:

  C25H20F3N5O2

• Molecular Weight:

  479.45

• References & Citations:

  [1]Luc J. Farmer, et al. Imidazopyridazines useful as inhibitors of the par-2 signaling pathway. WO. WO2015048245 A1. 2014-09-25.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [313986-65-1]