PAR-2-IN-2

• Target:

  Protease-activated Receptor|||Serine Protease

• Related Pathways:

  Proteases/Proteasome|||GPCR/G Protein

• Bioactivity:

  PAR-2-IN-2 (compound P-596) is an inhibitor of protease-activated receptor 2 (PAR-2), with an IC50 of 10.79 ?M for SLIGKV and an IC50 greater than 200 ?M for trypsin.

• Smiles:

  O=C (C1=NN2C (N=C (C=C2C (F) (F) F) C=3C=CC=CC3) =C1) N4CCN (C (=O) C=5C=CC=CC5) CC4

• Molecular Formula:

  C25H20F3N5O2

• Molecular Weight:

  479.454

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  313986-65-1