PAR 4 (1-6) (human)

• UNSPSC Description:

  PAR 4 (1-6) human, a hexapeptide, is a fragment of protease-activated receptor 4 (PAR4). PAR 4 (1-6) TFA acts as a PAR4-specific agonist[1].

• Target Antigen:

  Protease Activated Receptor (PAR)

• Type:

  Peptides

• Related Pathways:

  GPCR/G Protein

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/par-4-1-6-human.html

• Solubility:

  10 mM in DMSO

• Smiles:

  OC(C=C1)=CC=C1C[C@H](NC(CN)=O)C(N2[C@@H](CCC2)C(NCC(N[C@@H](CCC(N)=O)C(N[C@H](C(O)=O)C(C)C)=O)=O)=O)=O

• Molecular Weight:

  619.67

• References & Citations:

  [1]H Andersen, et al. Protease-activated receptor 1 is the primary mediator of thrombin-stimulated platelet procoagulant activity. Proc Natl Acad Sci U S A. 1999 Sep 28;96(20):11189-93.|[2]E Bretschneider, et al. Evidence for functionally active protease-activated receptor-4 (PAR-4) in human vascular smooth muscle cells. Br J Pharmacol. 2001 Apr;132(7):1441-6.

• Shipping Conditions:

  Room temperature

• Clinical Information:

  No Development Reported

• CAS Number:

  225779-44-2