Vaccarin C

• Description :

  Vaccarin C (Compound VIII) is a cycloheptapeptide with good antifungal activity against pathogenic fungi and dermatophytes M. audouinii and T. mentagrophytes with MIC values of 6 µg/mL. Vaccarin C also has high cytotoxicity against Dalton's lymphoma ascites (DLA) and Ehrlich's ascites carcinoma (EAC) cell lines with IC50 values of 3.35 and 5.72 μM, respectively[1].

• UNSPSC :

  12352209

• Target :

  Fungal

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Infection

• Smiles :

  O=C(N1[C@@](C(NCC(N[C@H](C(N[C@H](C(N2[C@](CCC2)([H])C(N[C@H](C(N3)=O)CC(C)C)=O)=O)C(C)C)=O)CC4=CC=C(C=C4)O)=O)=O)([H])CCC1)[C@@H]3CC5=CNC6=CC=CC=C56

• Molecular Formula :

  C43H56N8O8

• Molecular Weight :

  812.95

• References & Citations :

  [1]Dahiya R, et al. Synthesis and pharmacological investigation of segetalin C as a novel antifungal and cytotoxic agent. Arzneimittelforschung. 2008;58 (1) :29-34.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [177602-12-9]