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FGFR1 inhibitor-14

CAT: 0804-HY-169623Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-169623Size:1 Each
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Description
FGFR1 inhibitor-14 (compound 28) is a FGFR1 inhibitor, which can be used in anti-cancer research[1].
CAS Number
442534-83-0
UNSPSC
12352211
Target
FGFR
Related Pathways
Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
O=C(C1=C(NS(=O)(C2=CC=C3NC(C4=CC=CC2=C34)=O)=O)C=CC=C1)O
Molecular Formula
C18H12N2O5S
Molecular Weight
368.36
References & Citations
[1]Gryshchenko AA, et al. Design, synthesis and biological evaluation of naphthostyril derivatives as novel protein kinase FGFR1 inhibitors. J Enzyme Inhib Med Chem. 2015 Feb;30 (1) :126-32.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

2-(2-Oxo-1,2-dihydro-benzo[cd]indole-6-sulfonylamino)-benzoic acid
CAS Number442534-83-0
PubChem CID1720676
IUPAC Name2-[(2-oxo-1H-benzo[cd]indol-6-yl)sulfonylamino]benzoic acid
Molecular FormulaC18H12N2O5S
Molecular Weight368.4
XLogP2.7
Topological Polar Surface Area121
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Heavy Atom Count26
Formal Charge0
Complexity688
SMILES
C1=CC=C(C(=C1)C(=O)O)NS(=O)(=O)C2=C3C=CC=C4C3=C(C=C2)NC4=O
InChI
InChI=1S/C18H12N2O5S/c21-17-12-6-3-5-11-15(9-8-14(19-17)16(11)12)26(24,25)20-13-7-2-1-4-10(13)18(22)23/h1-9,20H,(H,19,21)(H,22,23)
InChIKey
TYNXIZLQXIBWGQ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 2-(2-Oxo-1,2-dihydro-benzo[cd]indole-6-sulfonylamino)-benzoic acid
CAS: 442534-83-0
CID: 1720676
Formula: C18H12N2O5S
MW: 368.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight368.4
XLogP32.7
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count4
Exact Mass368.04669266
Monoisotopic Mass368.04669266
Topological Polar Surface Area121 Ų
Heavy Atom Count26
Formal Charge0
Complexity688
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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